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Segue Clinic

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Methadone is a long-acting opioid medication used to treat opioid dependence.

What does Methadone do?

Methadone is a long-acting opioid medication used to treat opioid dependence. Methadone maintenance treatment prevents withdrawal and reduces or eliminates drug cravings and difficult physical withdrawal symptoms.

What is the goal of treatment?

Our goal is to help people who are dependent on illicit opioid drugs receive the comprehensive treatment they need. We can help you deal with your immediate crisis, become stable and improve your health, relationships and overall quality of life.

What does Methadone look like?

Pure Methadone is a white crystal powder that’s usually dissolved in an orange-flavoured drink and swallowed once a day. Initially, you will drink the medication at the pharmacy but as your treatment progresses you may be able to take your daily drink at home.

Is Methadone safe in pregnancy?

Pregnant women who are addicted to opioids are able to use methadone. By combining your Methadone treatment with regular prenatal care, you’ll increase the chances of having a healthy child. There are no known long-term effects of Methadone on the baby.

How does methadone make you feel?

Our patients in treatment tell us that being on Methadone makes them feel so normal that they can work, go to school and care for families without difficulty. Once your dose is adjusted properly, no one will be able to tell you are taking Methadone.

What are the side effects?

Some people experience mild side effects such as sweating and constipation but your physician will help you manage any problems.

How long does Methadone last?

A single dose of Methadone can eliminate withdrawal symptoms for 24 hours. When it’s time to finish your treatment, the Methadone dose will be tapered gradually to prevent withdrawal.

If Methadone is stopped abruptly, you may experience symptoms such as sweats, stomach cramps, diarrhea and body aches lasting for several days. We’ll help you cope until they subside.

Is Methadone dangerous?

When Methadone is taken as prescribed, it is very safe; however, it is a powerful drug and can be extremely dangerous for those who do not take it regularly. Even a small amount may be fatal for a child. For this reason, the dispensing of Methadone is carefully monitored and controlled.

Is Methadone addictive?

People in Methadone treatment do become tolerant to certain effects of the drug and will experience withdrawal if they don’t take their regular dose. It’s important to remember, however, that addiction is an uncontrollable dependency which is very different from the stability of a methadone maintenance program.

What are the long-term effects of methadone?

Methadone maintenance is a long-term treatment that is medically safe and effective for opioid dependence. It has been used successfully for over forty years and no long-term effects are known. 

Clinic Locations


80 Main Street West
Grimsby, ON, L3M 1R6

T: 905-688-1827, ext 9
F: 905-309-5358


554 Main Street East
Hamilton, ON, L8G 4A8

T: 905-688-1827, ext. 2
F: 905-522-0444

Niagara Falls

4632 Victoria Avenue
Niagara Falls, Ontario, L2E 4B7

T: 905-688-1827, ext. 4
F: 905-358-6413

Port Colborne

200 Catharine Street
Port Colborne, ON, L3K 4K8

T: 905-688-1827, ext 3
F: 905-834-1001

St. Catharines

61 James Street
St. Catharines, ON, L2R 5B9

T: 905-688-1827, ext 5
F: 905-688-7283

Stoney Creek

840 Queenston Rd, Unit 826
Stoney Creek, ON, L8G 4A8

T: 905-688-1827, ext. 6
F: 905-664-1359


8 Clairmont Street, Unit 1
Thorold, ON, L2V 1R1

T: 905-688-1827, ext 8
F: 905-680-9898


816 East Main Street
Welland, ON, L3B 3Y7

T: 905-688-1827, ext 7
F: 905-788-3040